Cellular Dynamics International Reprograms Blood Cells into Stem Cells

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July 8 /PRNewswire/ -- Researchers at report the ability to generate pluripotent stem cells, which have the ability to generate all tissue types in the body, from very smal volumes of ordinary human blood This significant breakthrough provides a readilyt obtainable source of pluripotent stem cells from the millionsw of samples in storage at blood repositories and healthcarwe institutions worldwide. These announced today, will be presented durinfg a poster session beginningat 4:45 p.m. on July 10 at the ISSCtR annual meetingin Barcelona, Spain.
"Industry's challenge was to reliablhy create iPS cells from a commonly available and easily accessible tissue source and we focused on storedr human peripheralblood samples," said , chief commercia l officer of CDI. "Generating pluripotent stem cells from small volumes of either freshly collected from a patient or accesserd from bloodstorage repositories, providezs a convenient source for generating patient-specific stem cells that are valuabler research tools and may one day be used as a cellulare therapy to treat disease.
" , chief operationsx officer of CDI, said, "The abilit y to use common tissue repositoriex to create iPS cells from donors with known medical history enables us to provide the pharmaceuticall industry with a cell portfolio representing individual disease models, retrospective analysis and ethnifc diversity. This is the firsr step in paving the wayfor large-scale processingg and industrialization of iPS cells." To generate the inducerd pluripotent stem (iPS) cells, CDI scientists isolated a type of white blood cell, from a 3 ml donorf blood sample. The cells were stimulated, expanded and exposed to documentedfreprogramming factors. iPS cell coloniesx were observed afterthree weeks.
Analysis revealed that the iPS cell s are functionally identical to embryonic stem cells and iPS cellsw generated from other humantissue sources, that they carry the same genetic backgrouncd as the source bloofd sample, and that they have the pluripotenty ability to differentiate into any cell type. Abouty Cellular Dynamics International, Inc. Cellular Dynamicd International, Inc. (CDI) is a leadinyg developer of next-generation stem cell technologies for drug developmentr and personalizedmedicine applications. CDI harnesses the power of pluripotenr stem cells and theit ability to differentiate into any cell typefor world-clasa drug development tools.
In addition, it is the leader in iPS the production of pluripotent stem cell lines from adult CDI was founded in 2004by , a pioneetr in human embryonic stem cell research at the Universitty of Wisconsin-Madison, and Tactics II Ventures, a Wisconsin-basede venture capital fund. CDI's facilities are locaterd in Madison, Wisconsin. See . MEDIwA CONTACTS: Joleen Rau Senior Marketing & Communications Cellular Dynamicw International, Inc. (608) 310-5142 jrau@cellulardynamics.com Robert E. Ph.D. robert.flamm@russopartnersllc.com 212-845-4226 Tony Russo tony.russo@russopartnersllc.
com 212-845-4251